Once diagnosed (usually within 3 to 5 days of birth), a newborn is referred to a PKU specialist. In Minnesota, PKU patients may be referred to the University of Minnesota PKU Clinic, or the Mayo Clinic. The children are placed on a highly restricted and carefully monitored diet including a protein supplement.  The supplement comes in many forms but a formula is the most common treatment for children with PKU. Treatment also includes routine exams to track growth and overall health; blood tests/evaluations and regular developmental assessments performed by licensed psychologists. The individual health plan is adjusted as necessary throughout the life of the individual with PKU.